Data Release 29 Highlight

Clinical Trials in Organ Transplantation (CTOT)ImmPort’s latest data release contains 20 shared studies, covering multiple assay types and focus areas. Three of the shared studies come from the Clinical Trials in Organ Transplantation (CTOT) and Clinical Trials in Organ Transplantation in Children (CTOT-C) programs. These vital programs are sponsored by the National Institutes of Health, National Institute of Allergy and Infectious Diseases division, and aim to “improve short and long-term graft and patient survival.”To learn more, check out these key facts, or follow the links to view study details within ImmPort:

Study SDY1095: A Retrospective Multicenter Study to Determine 4-Year Clinical Outcomes in Subjects Previously Enrolled in the CTOT-05 Study

Subjects: 180

Assessment Data: Graft function

Description: A multicenter, non-randomized, retrospective study to collect long term (4 years post-transplant) clinical outcome data on subjects previously enrolled in the CTOT-05 study

Study SDY960: Viral Triggers of Alloimmunity and Autoimmunity in Pediatric Lung Transplantation

Subjects: 78

Assay Types: HLA Typing

Description: A non-randomized observational study to determine whether respiratory viral infections increase the risk of bronchiolitis obliterans syndrome, obliterative bronchiolitis, death or retransplantation in pediatric lung transplant recipients

Study SDY1295: Perceived Barriers to Patient Adherence after Pediatric Solid Organ Transplantation

Subjects: 502

Description: A two part prospective, observational, multi-center cohort study of solid organ transplant recipients

Part 1: A cross sectional comparison of perceived barriers to adherence to post-transplant immunosuppressant regimens in parents of children (0-11 years) versus adolescents (12-21 years)

Part 2: A longitudinal study to evaluate whether perceived barriers to adherence increase with time during the first year following transplantation

For more information on studies within Data Release 29, check out these Data Release Notes.