ImmPort team members, @ImmPortDB, and collaborators were thrilled to host a series of talks and a hands-on workshop during the 2019 Federation of Clinical Immunology Societies (FOCIS) Annual Meeting. The action packed session was chaired by ImmPort Scientific Program Director, Sanchita Bhattacharya, @SanchitaB, PhD and Bioinformatics Project Lead of the Bakar Institute of Computational Health Sciences, UCSF, and included several enlightening presentations from ImmPort collaborators and team members: Precision Immunology: How High Parameter Technology Can Shape Immunotherapy; Pratip K.

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The International Society for Advancement of Cytometry will hold its 34th annual congress in Vancouver, Canada on June 22-26, 2019. This distinguished event known as CYTO, features world renowned speakers, workshops, scientific tutorials, and technology showcases in the area of cytometry. ImmPort’s own Atul Butte, MD, PhD and Director of the Bakar Computational Health Sciences Institute at UCSF, will be speaking on the topic of Translating a Trillion Points of Data into Therapies, Diagnostics, and New Insights into Immunology on June 23rd.

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In order to understand and study immune dysfunction, it is vital to understand how the immune system functions in healthy individuals. Dr. Sanchita Bhattacharya, ImmPort Scientific Program Director and Bioinformatics Project Leader at University of California San Francisco, presented on exactly this topic at the 7th International Molecular Diagnostics Europe conference in Lisbon, Portugal. Previously, immune assays had not been reproducibly characterized for a sufficiently large and diverse healthy human cohort.

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Our IEDB collaborators on the HIPC Standards Working Group are presenting a poster at AAI 2019 on the work we’ve done to represent immune exposures with ontologies when the description of study subjects is uploaded to ImmPort. Abstract ID: 905 Program Number: 130.26 () Abstract Title: Formal representation of immunology related data with ontologies Session Title: Technological Innovations I Date: Saturday, May 11, 2019 Time: 2:30 PM - 3:45 PM Room: Exhibit/Poster Hall

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Data Release 29 Highlight

Clinical Trials in Organ Transplantation (CTOT)ImmPort’s latest data release contains 20 shared studies, covering multiple assay types and focus areas. Three of the shared studies come from the Clinical Trials in Organ Transplantation (CTOT) and Clinical Trials in Organ Transplantation in Children (CTOT-C) programs. These vital programs are sponsored by the National Institutes of Health, National Institute of Allergy and Infectious Diseases division, and aim to “improve short and long-term graft and patient survival.

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ImmPort Published

ImmPort published in Nature - Scientific Data! Welcome to the ImmPort blog! This is our inaugural blog post and we are going to use this space to highlight our recent publication in Nature - Scientific Data. Whether you are one of our many dedicated and skilled data providers, experienced ImmPort shared data user or an ImmPort novice; we recommend you read the publication. What sorts of information will you find in “ImmPort, toward repurposing of open access immunological assay data for translational and clinical research”?

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Get funded to use ImmPort Data

Did you know NIAID funds researchers to develop new or improved ways to use ImmPort shared data? The Cooperative Agreement PAR-16-253, posted in May 2016, does just that. For those of you pondering the possibilities, a brief summary of the first and second round awardees follows. 2017 Dr. Steve Kleinstein’s team at Yale University is developing LinkedImm, a system designed to integrate ImmPort vaccine studies, linking those studies to other public resources such as pathway databases, gene ontology and publications, to support hypothesis-driven queries.

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HIPC 2018 Sub-committee meeting blog

December 2018 HIPC Subcommittee Meeting The Human Immune Profiling Consortium HIPC 2018 Subcommittee annual meeting provided an opportunity for the Assay, Bioinformatics and Clinical subcommittees to report on their progress, discuss goals, and refine implementation details. ImmPort works with the HIPC committees to implement their recommendations and guidelines for data acquisition descriptions. The recent addition of immune exposures descriptive attributes for subjects was a collaboration with the bioinformatics and clinical groups to use ontological terms to describe the nature of immune exposures in terms of vaccination, disease, vaccine type and subject disease status.

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The ImmPort team successfully hosted a workshop at the FOCIS conference this past June in San Francisco. The focus of the workshop was “Big Data in Immunology,” and included both an invited speaker session and a hands-on workshop. This was quite a successful workshop for ImmPort, with 51 people attending, the largest number we have hosted to date! The first part of the workshop included a series of invited speakers, all of whom came from different organizations and universities, offering insights on many different topics.

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The Accelerating Medicines Partnership (AMP) program, a public-private effort aimed at improving the identification of drug targets and speed the development of new drugs. Participants include the National Institutes of Health (NIH), Foundation for NIH, biopharmaceutical firms as well as non-profit organizations The NIH announced on February 21, 2018 in the NIH News Release the release of AMP data from ImmPort. Data from the Lupus and Rheumatoid Arthritis (AMP/SLE) pilot projects is now available in ImmPort as SDY997, SDY998 & SDY999.

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